Functionalization of oligosaccharide mimetics and multimerization using squaric diester-mediated coupling.
نویسندگان
چکیده
Functionalized carbohydrate-centered glycoclusters formed the starting material for the synthesis of tagged oligosaccharide and glycoconjugate mimetics, which were obtained by thiourea-bridging, peptide coupling and in particular squaric diester-mediated coupling. The latter method could also be utilized to provide new multivalent glycoconjugates, which were tested for their anti-adhesive properties in an ELISA with Escherichia coli bacteria.
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ورودعنوان ژورنال:
- Carbohydrate research
دوره 342 5 شماره
صفحات -
تاریخ انتشار 2007